Miss Promiscuity will take on the males in the Group Three Heath at Caulfield instead of racing against her own sex in the Cockram Stakes.
Tom Dabernig, who trains in partnership with David and Ben Hayes, said Miss Promiscuity had freshened up well following a two-run Adelaide campaign which followed successive Caulfield victories during the autumn.
She failed to finish in the first of her two Morphettville outings when Luke Nolen came off and suffered serious injuries in the Sangster Stakes.
Miss Promiscuity will be having her first start since she finished 12th to Black Heart Bart in the Goodwood on May 21.
"She's been flying at home and she's got a great record at the track and trip," Dabernig said.
"On how she's been going we think taking on the boys she should give the race a shake."
Stable newcomer Jessy Belle and Kayjay's Joy will represent Lindsay Park in the Cockram, a 1200m contest for mares.
Miss Promiscuity defeated Sabatini and Tycoon Tara over Saturday's 1100m-course before getting the better of Jalan Jalan and The Quarterback over 1200m in April.
Dabernig said the stable had decided to wait another week with Keen Array, also an entry for The Heath.
Keen Array was a late scratching from last Saturday's Carlyon Stakes at Moonee Valley after suffering an attack of colic when being saddled for the race.
The gelding had been working and trialling well in preparation for his first run since finishing third at Moonee Valley during the autumn.
Dabernig said Keen Array would line up in a jump-out at Flemington on Thursday morning before contesting the Group Two McEwen Stakes (1000m) at Moonee Valley on September 3.
G3 - The Majordomo Hospitality Handicap Steeple Chase
G2 - Prix Raoul Balliere
G2 - Prix Ariste Hemard
G3 - Victress Stakes
G2 - Premier Trophy